June 27, 2010

MRCP 2 Question 3

Cytogenetic abnormalities are a known side effect of several cytotoxic drugs.

Which of the following cytotoxic drugs is most likely to lead to endometrial cancer ?

a) tamoxifen
b) 5-fluorouracil
c) taxoids
d) cyclopentenyl cytosine
e) trastuzumab

The correct answer is A


Long term use of tamoxifen has been associated with an increase in endometrial cancer.

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