Concerning inflammatory and allergic reactions

A certain type of cell plays a central role in inflammatory and immediate allergic reactions and settles in connective tissues and usually does not circulate in the blood stream.

This type of cell is known as a:

a) Basophil
b) Mast cell
c) Eosinophil
d) Neutrophil
e) Macrophage






ANSWER
The correct answer is B


Explanation
Mast cells and basophils play a central role in inflammatory and immediate allergic reactions. They are able to release potent inflammatory mediators, such as histamine, proteases, chemotactic factors, cytokines and metabolites of arachidonic acid that act on the vasculature, smooth muscle, connective tissue, mucous glands and inflammatory cells.

Mast cells settle in connective tissues and usually do not circulate in the blood stream.

Basophils are the smallest circulating granulocytes with relatively the least known function. They arise in the bone marrow, and following maturation and differentiation, are released into the blood circulation. If they are adequately stimulated they may settle in the tissues.

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